Other names for Turner’s syndrome include monosomy X, 45X and Ullrich-Turner syndrome.
What is the scientific name for Turner syndrome?
Turner syndrome is a genetic condition caused by an abnormality on one of your sex chromosomes. It’s also called monosomy X, gonadal dysgenesis, and Bonnevie-Ullrich syndrome.
What are the two types of Turner syndrome?
There are 2 types of Turner syndrome: monosomy X TS and mosaic TS. About half of all girls with Turner syndrome have a monosomy disorder. Monosomy means that a person is missing one chromosome in the pair. Instead of 46 chromosomes, the person has only 45 chromosomes.
What disease is similar to Turner syndrome?
In fact, because some individuals with Noonan syndrome may superficially resemble those with Turner syndrome (due to certain findings that may be associated with both disorders, such as short stature, webbed neck, etc.), Noonan syndrome has in the past been referred to as “male Turner syndrome,” “female pseudo-Turner
Why is it called Turner syndrome?
Turner syndrome is named for Henry Turner who, in 1938, was one of the first doctors to report on the disorder in the medical literature. Turner syndrome is one of the most common chromosomal disorders and likely the most common genetic disorder of females.
What is Turner syndrome genotype?
The classic cause of the disease is the complete absence of a second sex chromosome, leading to an abnormal 45,X karyotype, as opposed to the normal 46,XX or 46,XY karyotypes (Ford et al. 1959). The murine model for Turner Syndrome is the XO mouse.
Can you live with Monosomy?
In most cases, embryos with monosomy of the autosomes or sex chromosomes are not viable. Some individuals with monosomy of the sex chromosomes (45XO genotype) can survive, however (Figure 6). Such individuals, who are said to have Turner’s syndrome, exhibit a female phenotype, but the gonads are sterile.
What famous person has Turner syndrome?
Actress Linda Hunt and gymnast Misty Marlowe, Scottish actress Janette Cranky have Turner’s syndrome.
Why does Turner syndrome only affect females?
The condition only occurs in females. Most commonly, a female with Turner syndrome has only 1 X chromosome. Others may have 2 X chromosomes, but one of them is incomplete. Sometimes, a female has some cells with 2 X chromosomes, but other cells have only 1.
What race is Turner syndrome most common in?
During 2012-2016 (average) in North Carolina, Turner syndrome was highest for American Indian infants (5.1 in 10,000 live female births), followed by whites (2.3 in 10,000 live female births), Hispanics (1.8 in 10,000 live female births), blacks (1.1 in 10,000 live female births) and Asians (0.8 in 10,000 live female
What is the difference between Turner syndrome and mosaic Turner syndrome?
In classical Turner syndrome, an X chromosome is completely missing. This affects about half of all people with TS. Mosaic Turner syndrome, mosaicism, or Turner mosaicism is where the abnormalities occur only in the X chromosome of some of the body’s cells.
What is t13?
Trisomy 13, also called Patau syndrome, is a chromosomal condition associated with severe intellectual disability and physical abnormalities in many parts of the body.
Why can’t males have Turner syndrome?
Turner syndrome is caused by a female having one normal X chromosome in each of her cells, while the other sex chromosome is either missing or structurally abnormal. Females without Turner syndrome have 2 full X chromosome in all of their cells, and males have one X chromosome and one Y chromosome.
Where did the name for Turner syndrome discovered?
The syndrome is named after Henry Turner, an endocrinologist from Illinois, who described it in 1938. In Europe, it is often called Ullrich–Turner syndrome or even Bonnevie–Ullrich–Turner syndrome to acknowledge that earlier cases had also been described by European doctors.
Can a woman with Turner syndrome get pregnant?
Spontaneous puberty occurs in 5-10% of women with Turner’s syndrome, and 2-5% of them become pregnant spontaneously. Sexually active young women with Turner’s syndrome need contraception. It can be administered as contraceptive pills, which also serve as HRT.
What is the karyotype of Turner syndrome?
Turner syndrome is sporadic. A majority of cases ascertained prenatally have a 45,X karyotype. Paternal nondisjunction accounts for ∼70% of liveborn cases with a 45,X.